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Non-steroidal anti-inflammatory drug induced acute kidney injury in the community dwelling general population and people with chronic kidney disease: systematic review and meta-analysis

Overview of attention for article published in BMC Nephrology, August 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#26 of 2,342)
  • High Attention Score compared to outputs of the same age (93rd percentile)

Mentioned by

news
2 news outlets
policy
1 policy source
twitter
24 tweeters
googleplus
1 Google+ user
reddit
1 Redditor

Citations

dimensions_citation
117 Dimensions

Readers on

mendeley
196 Mendeley
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Title
Non-steroidal anti-inflammatory drug induced acute kidney injury in the community dwelling general population and people with chronic kidney disease: systematic review and meta-analysis
Published in
BMC Nephrology, August 2017
DOI 10.1186/s12882-017-0673-8
Pubmed ID
Authors

Xinyu Zhang, Peter T Donnan, Samira Bell, Bruce Guthrie

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are a common cause of adverse drug events (ADEs), but renal risks of NSAIDs are less well quantified than gastrointestinal and cardiac risks. This paper reports a systematic review of published population-based observational studies examining the risk of acute kidney injury (AKI) associated with NSAIDs in community-dwelling adults and those with pre-existing chronic kidney disease (CKD). MEDLINE and EMBASE databases were searched until June 2016, and 3789 papers screened. Ten studies reporting NSAID risk of AKI in the general population were included in random effects meta-analysis, of which five additionally reported NSAID risk in people with CKD. In the general population, the pooled odds ratio (OR) of AKI for current NSAID exposure was 1.73 (95%CI 1.44 to 2.07), with somewhat higher risk observed in older people (OR 2.51, 95%CI 1.52 to 2.68). In people with CKD, individual study OR of AKI due to current NSAID exposure ranged from 1.12 to 5.25, with pooled estimate OR 1.63 (95% CI 1.22 to 2.19). No study reported baseline risk of AKI in different populations meaning absolute risks could not be estimated, but baseline risk and therefore the absolute risk of NSAID exposure is likely to be higher in people with CKD and older people. Large population based studies measuring AKI using current definitions and estimating the absolute risk of harm are needed in order to better inform clinical decision making.

Twitter Demographics

The data shown below were collected from the profiles of 24 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 196 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 196 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 26 13%
Other 17 9%
Student > Ph. D. Student 17 9%
Student > Master 17 9%
Researcher 13 7%
Other 40 20%
Unknown 66 34%
Readers by discipline Count As %
Medicine and Dentistry 59 30%
Pharmacology, Toxicology and Pharmaceutical Science 17 9%
Nursing and Health Professions 15 8%
Biochemistry, Genetics and Molecular Biology 8 4%
Veterinary Science and Veterinary Medicine 2 1%
Other 20 10%
Unknown 75 38%

Attention Score in Context

This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2020.
All research outputs
#818,469
of 21,431,229 outputs
Outputs from BMC Nephrology
#26
of 2,342 outputs
Outputs of similar age
#18,873
of 289,161 outputs
Outputs of similar age from BMC Nephrology
#1
of 1 outputs
Altmetric has tracked 21,431,229 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,342 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,161 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them