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Risk markers for fatal and non-fatal prescription drug overdose: a meta-analysis

Overview of attention for article published in Injury Epidemiology, August 2017
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)

Mentioned by

10 tweeters


65 Dimensions

Readers on

103 Mendeley
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Risk markers for fatal and non-fatal prescription drug overdose: a meta-analysis
Published in
Injury Epidemiology, August 2017
DOI 10.1186/s40621-017-0118-7
Pubmed ID

Joanne E. Brady, Rebecca Giglio, Katherine M. Keyes, Charles DiMaggio, Guohua Li


Drug overdose is a public health crisis in the United States, due in part to the unintended consequences of increases in prescribing of opioid analgesics. Many clinicians evaluate risk markers for opioid-related harms when prescribing opioids for chronic pain; however, more data on predictive risk markers are needed. Risk markers are attributes (modifiable and non-modifiable) that are associated with increased probability of an outcome. This review aims to identify risk markers associated with fatal and non-fatal prescription drug overdose by synthesizing findings in the existing peer-reviewed and grey literature. Eligible cohort, case-control, cross-sectional, and case-cohort studies were reviewed and data were extracted for qualitative and quantitative synthesis. Summary odds ratios (SOR) were estimated from 29 studies for six risk markers: sex, age, race, psychiatric disorders, substance use disorder (SUD), and urban/rural residence. Heterogeneity was assessed and effect estimates were stratified by study characteristics. Of the six risk markers identified, SUD had the strongest association with drug overdose death (SOR = 5.24, 95% confidence interval (CI) = 3.53 - 7.76), followed by psychiatric disorders (SOR = 3.94, 95% CI = 3.09 - 5.01), white race (SOR = 2.28, 95% CI = 1.93 - 2.70), the 35-44 year age group relative to the 25-34 year reference group (SOR = 1.52, 95% CI = 1.31 - 1.76), and male sex (SOR = 1.33, 95% CI = 1.17 - 1.51). This review highlights fatal and non-fatal prescription drug risk markers most frequently assessed in peer-reviewed and grey literature. There is a need to better understand modifiable risk markers and underlying reasons for drug misuse in order to inform interventions that may prevent future drug overdoses.

Twitter Demographics

The data shown below were collected from the profiles of 10 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 103 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 103 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 21 20%
Researcher 11 11%
Student > Ph. D. Student 9 9%
Other 8 8%
Student > Doctoral Student 6 6%
Other 25 24%
Unknown 23 22%
Readers by discipline Count As %
Medicine and Dentistry 19 18%
Nursing and Health Professions 11 11%
Social Sciences 10 10%
Pharmacology, Toxicology and Pharmaceutical Science 8 8%
Neuroscience 5 5%
Other 20 19%
Unknown 30 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2017.
All research outputs
of 21,636,364 outputs
Outputs from Injury Epidemiology
of 299 outputs
Outputs of similar age
of 289,736 outputs
Outputs of similar age from Injury Epidemiology
of 1 outputs
Altmetric has tracked 21,636,364 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 299 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.0. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,736 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them