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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The role of melatonin in the onset and progression of type 3 diabetes
|
|---|---|
| Published in |
Molecular Brain, August 2017
|
| DOI | 10.1186/s13041-017-0315-x |
| Pubmed ID | |
| Authors |
Juhyun Song, Daniel J. Whitcomb, Byeong C. Kim |
| Abstract |
Alzheimer's disease (AD) is defined by the excessive accumulation of toxic peptides, such as beta amyloid (Aβ) plaques and intracellular neurofibrillary tangles (NFT). The risk factors associated with AD include genetic mutations, aging, insulin resistance, and oxidative stress. To date, several studies that have demonstrated an association between AD and diabetes have revealed that the common risk factors include insulin resistance, sleep disturbances, blood brain barrier (BBB) disruption, and altered glucose homeostasis. Many researchers have discovered that there are mechanisms common to both diabetes and AD. AD that results from insulin resistance in the brain is termed "type 3 diabetes". Melatonin synthesized by the pineal gland is known to contribute to circadian rhythms, insulin resistance, protection of the BBB, and cell survival mechanisms. Here, we review the relationship between melatonin and type 3 diabetes, and suggest that melatonin might regulate the risk factors for type 3 diabetes. We suggest that melatonin is crucial for attenuating the onset of type 3 diabetes by intervening in Aβ accumulation, insulin resistance, glucose metabolism, and BBB permeability. |
X Demographics
The data shown below were collected from the profiles of 29 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 7% |
| Spain | 2 | 7% |
| United Kingdom | 2 | 7% |
| New Zealand | 1 | 3% |
| Iceland | 1 | 3% |
| Brazil | 1 | 3% |
| Czechia | 1 | 3% |
| Unknown | 19 | 66% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 22 | 76% |
| Practitioners (doctors, other healthcare professionals) | 4 | 14% |
| Scientists | 2 | 7% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 111 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 19 | 17% |
| Student > Master | 14 | 13% |
| Student > Ph. D. Student | 11 | 10% |
| Researcher | 10 | 9% |
| Student > Doctoral Student | 5 | 5% |
| Other | 17 | 15% |
| Unknown | 35 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 21% |
| Biochemistry, Genetics and Molecular Biology | 13 | 12% |
| Neuroscience | 6 | 5% |
| Agricultural and Biological Sciences | 5 | 5% |
| Nursing and Health Professions | 5 | 5% |
| Other | 18 | 16% |
| Unknown | 41 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2023.
All research outputs
#1,923,319
of 25,545,162 outputs
Outputs from Molecular Brain
#45
of 1,201 outputs
Outputs of similar age
#36,359
of 327,911 outputs
Outputs of similar age from Molecular Brain
#3
of 22 outputs
Altmetric has tracked 25,545,162 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,201 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,911 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.