Title |
Lactate Dehydrogenase A is a potential prognostic marker in clear cell renal cell carcinoma
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Published in |
Molecular Cancer, May 2014
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DOI | 10.1186/1476-4598-13-101 |
Pubmed ID | |
Authors |
Hala Girgis, Olena Masui, Nicole MA White, Andreas Scorilas, Fabio Rotondo, Annetta Seivwright, Manal Gabril, Emily R Filter, Andrew HA Girgis, Georg A Bjarnason, Michael AS Jewett, Andrew Evans, Sahar Al-Haddad, KW Michael Siu, George M Yousef |
Abstract |
Over 90% of cancer-related deaths in clear cell renal cell carcinoma (RCC) are caused by tumor relapse and metastasis. Thus, there is an urgent need for new molecular markers that can potentiate the efficacy of the current clinical-based models of prognosis assessment. The objective of this study is to evaluate the potential significance of lactate dehydrogenase A (LDHA), assessed by immunohistochemical staining, as a prognostic marker in clear cell renal cell carcinoma in relation to clinicopathological features and clinical outcome. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | <1% |
Unknown | 138 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 37 | 27% |
Student > Ph. D. Student | 16 | 12% |
Researcher | 15 | 11% |
Other | 7 | 5% |
Student > Postgraduate | 7 | 5% |
Other | 25 | 18% |
Unknown | 32 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 35 | 25% |
Medicine and Dentistry | 27 | 19% |
Biochemistry, Genetics and Molecular Biology | 18 | 13% |
Immunology and Microbiology | 5 | 4% |
Chemistry | 4 | 3% |
Other | 12 | 9% |
Unknown | 38 | 27% |