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Cytokine responsiveness of CD8+ T cells is a reproducible biomarker for the clinical efficacy of dendritic cell vaccination in glioblastoma patients

Overview of attention for article published in Journal for Immunotherapy of Cancer, May 2014
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2 X users

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39 Mendeley
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Title
Cytokine responsiveness of CD8+ T cells is a reproducible biomarker for the clinical efficacy of dendritic cell vaccination in glioblastoma patients
Published in
Journal for Immunotherapy of Cancer, May 2014
DOI 10.1186/2051-1426-2-10
Pubmed ID
Authors

Richard G Everson, Richard M Jin, Xiaoyan Wang, Michael Safaee, Rudi Scharnweber, Dominique N Lisiero, Horacio Soto, Linda M Liau, Robert M Prins

Abstract

Immunotherapeutic approaches, such as dendritic cell (DC) vaccination, have emerged as promising strategies in the treatment of glioblastoma. Despite their promise, however, the absence of objective biomarkers and/or immunological monitoring techniques to assess the clinical efficacy of immunotherapy still remains a primary limitation. To address this, we sought to identify a functional biomarker for anti-tumor immune responsiveness associated with extended survival in glioblastoma patients undergoing DC vaccination.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 5%
Korea, Republic of 1 3%
Unknown 36 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 18%
Researcher 7 18%
Student > Bachelor 6 15%
Student > Doctoral Student 3 8%
Other 2 5%
Other 5 13%
Unknown 9 23%
Readers by discipline Count As %
Medicine and Dentistry 12 31%
Biochemistry, Genetics and Molecular Biology 4 10%
Agricultural and Biological Sciences 4 10%
Neuroscience 3 8%
Immunology and Microbiology 2 5%
Other 2 5%
Unknown 12 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2016.
All research outputs
#15,437,813
of 25,782,917 outputs
Outputs from Journal for Immunotherapy of Cancer
#2,572
of 3,517 outputs
Outputs of similar age
#124,121
of 242,489 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#12
of 12 outputs
Altmetric has tracked 25,782,917 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,517 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,489 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.