Title |
Additional burden of asymptomatic and sub-patent malaria infections during low transmission season in forested tribal villages in Chhattisgarh, India
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Published in |
Malaria Journal, August 2017
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DOI | 10.1186/s12936-017-1968-8 |
Pubmed ID | |
Authors |
Mehul Kumar Chourasia, Kamaraju Raghavendra, Rajendra M. Bhatt, Dipak Kumar Swain, Hemraj M. Meshram, Jayant K. Meshram, Shrity Suman, Vinita Dubey, Gyanendra Singh, Kona Madhavinadha Prasad, Immo Kleinschmidt |
Abstract |
The burden of sub-patent malaria is difficult to recognize in low endemic areas due to limitation of diagnostic tools, and techniques. Polymerase chain reaction (PCR), a molecular based technique, is one of the key methods for detection of low parasite density infections. The study objective was to assess the additional burden of asymptomatic and sub-patent malaria infection among tribal populations inhabiting three endemic villages in Keshkal sub-district, Chhattisgarh, India. A cross-sectional survey was conducted in March-June 2016, during the low transmission season, to measure and compare prevalence of malaria infection using three diagnostics: rapid diagnostic test, microscopy and nested-PCR. Out of 437 individuals enrolled in the study, 103 (23.6%) were malaria positive by PCR and/or microscopy of whom 89.3% were Plasmodium falciparum cases, 77.7% were afebrile and 35.9% had sub-patent infections. A substantial number of asymptomatic and sub-patent malaria infections were identified in the survey. Hence, strategies for identifying and reducing the hidden burden of asymptomatic and sub-patent infections should focus on forest rural tribal areas using more sensitive molecular diagnostic methods to curtail malaria transmission. |
X Demographics
Geographical breakdown
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Unknown | 4 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 50% |
Science communicators (journalists, bloggers, editors) | 2 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 72 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 20 | 28% |
Student > Ph. D. Student | 9 | 13% |
Student > Master | 8 | 11% |
Lecturer | 4 | 6% |
Student > Doctoral Student | 4 | 6% |
Other | 9 | 13% |
Unknown | 18 | 25% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 13 | 18% |
Immunology and Microbiology | 7 | 10% |
Nursing and Health Professions | 7 | 10% |
Agricultural and Biological Sciences | 5 | 7% |
Biochemistry, Genetics and Molecular Biology | 4 | 6% |
Other | 9 | 13% |
Unknown | 27 | 38% |