Title |
The challenge of recruiting patients into a placebo-controlled surgical trial
|
---|---|
Published in |
Trials, May 2014
|
DOI | 10.1186/1745-6215-15-167 |
Pubmed ID | |
Authors |
Kristoffer B Hare, L Stefan Lohmander, Ewa M Roos |
Abstract |
Randomized placebo-controlled trials represent the gold standard in evaluating healthcare interventions but are rarely performed within orthopedics. Ethical concerns or well-known challenges in recruiting patients for surgical trials in general have been expressed and adding a placebo component only adds to this complexity. The purpose of this study was to report the challenges of recruiting patients into an orthopedic placebo-controlled surgical trial, to determine the number of patients needed to be screened and allocated in order to include one participant into the trial, and to identify reasons associated with participation in a placebo-controlled randomized surgical trial. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Norway | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 2 | 2% |
United States | 1 | 1% |
United Kingdom | 1 | 1% |
Unknown | 82 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 17 | 20% |
Student > Ph. D. Student | 10 | 12% |
Researcher | 9 | 10% |
Student > Postgraduate | 7 | 8% |
Student > Bachelor | 6 | 7% |
Other | 13 | 15% |
Unknown | 24 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 37 | 43% |
Nursing and Health Professions | 5 | 6% |
Sports and Recreations | 3 | 3% |
Social Sciences | 2 | 2% |
Agricultural and Biological Sciences | 1 | 1% |
Other | 7 | 8% |
Unknown | 31 | 36% |