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Interactomics profiling of the negative regulatory function of carbon monoxide on RANKL-treated RAW 264.7 cells during osteoclastogenesis

Overview of attention for article published in BMC Systems Biology, May 2014
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Title
Interactomics profiling of the negative regulatory function of carbon monoxide on RANKL-treated RAW 264.7 cells during osteoclastogenesis
Published in
BMC Systems Biology, May 2014
DOI 10.1186/1752-0509-8-57
Pubmed ID
Authors

Feng-Jen Tseng, Wei-Tso Chia, Jia-Fwu Shyu, Guo-Hau Gou, Huey-Kang Sytwu, Ching-Wu Hsia, Min-Jen Tseng, Ru-Yu Pan

Abstract

During osteoclastogenesis, the maturation of osteoclast (OC) progenitors is stimulated by the receptor activator of nuclear factor-κB ligand (RANKL). Excess OC production plays a critical role in the pathogenesis of inflammatory bone disorders. Conversely, the inhibition of abnormal OC proliferation reduces inflammation-induced bone loss. Low concentrations of carbon monoxide (CO) are known to decrease inflammation and OC-mediated bone erosion but the molecular mechanism is unknown.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 33%
Student > Ph. D. Student 2 22%
Student > Doctoral Student 1 11%
Student > Master 1 11%
Student > Postgraduate 1 11%
Other 0 0%
Unknown 1 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 33%
Biochemistry, Genetics and Molecular Biology 2 22%
Medicine and Dentistry 2 22%
Computer Science 1 11%
Unknown 1 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 May 2014.
All research outputs
#18,372,841
of 22,756,196 outputs
Outputs from BMC Systems Biology
#834
of 1,142 outputs
Outputs of similar age
#163,746
of 227,373 outputs
Outputs of similar age from BMC Systems Biology
#23
of 30 outputs
Altmetric has tracked 22,756,196 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,142 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,373 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.