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Gut dysbiosis in mice genetically selected for low antibody production

Overview of attention for article published in Gut Pathogens, August 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

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1 blog
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12 Mendeley
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Title
Gut dysbiosis in mice genetically selected for low antibody production
Published in
Gut Pathogens, August 2017
DOI 10.1186/s13099-017-0193-x
Pubmed ID
Authors

Ana Carolina da Silva Santos, José Ricardo Jensen, Silvio Luis de Oliveira, Josias Rodrigues

Abstract

Dysbiosis is linked to the cause of several human diseases, many of which having an immunity related component. This work investigated whether mice genetically selected for low or high antibody production display differences in intestinal bacterial communities, and consisted in the comparison of fecal 16SV6-V8 rDNA PCR amplicons resolved by temperature gradient gel electrophoresis (TGGE) of five each of low (LIII) and high (HIII) antibody producing mice. 16SV6 rDNA amplicons of 2 mice from each line were sequenced. LIII mice were grouped in a single TGGE cluster, displayed a low α-diversity, and were distinguished by low Firmicutes/Bacteroidetes ratio. The results suggest that genetically driven low antibody production in mice is associated with gut dysbiosis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 33%
Student > Doctoral Student 2 17%
Professor > Associate Professor 2 17%
Student > Master 1 8%
Lecturer > Senior Lecturer 1 8%
Other 0 0%
Unknown 2 17%
Readers by discipline Count As %
Immunology and Microbiology 3 25%
Medicine and Dentistry 2 17%
Agricultural and Biological Sciences 1 8%
Environmental Science 1 8%
Biochemistry, Genetics and Molecular Biology 1 8%
Other 1 8%
Unknown 3 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2017.
All research outputs
#3,707,445
of 22,997,544 outputs
Outputs from Gut Pathogens
#89
of 524 outputs
Outputs of similar age
#66,466
of 317,751 outputs
Outputs of similar age from Gut Pathogens
#3
of 15 outputs
Altmetric has tracked 22,997,544 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 524 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,751 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.