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Estrogen receptor α and aryl hydrocarbon receptor independent growth inhibitory effects of aminoflavone in breast cancer cells

Overview of attention for article published in BMC Cancer, May 2014
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  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

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Citations

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31 Mendeley
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Title
Estrogen receptor α and aryl hydrocarbon receptor independent growth inhibitory effects of aminoflavone in breast cancer cells
Published in
BMC Cancer, May 2014
DOI 10.1186/1471-2407-14-344
Pubmed ID
Authors

Ashley M Brinkman, Jiacai Wu, Karen Ersland, Wei Xu

Abstract

Numerous studies have implicated the aryl hydrocarbon receptor (AhR) as a potential therapeutic target for several human diseases, including estrogen receptor alpha (ERα) positive breast cancer. Aminoflavone (AF), an activator of AhR signaling, is currently undergoing clinical evaluation for the treatment of solid tumors. Of particular interest is the potential treatment of triple negative breast cancers (TNBC), which are typically more aggressive and characterized by poorer outcomes. Here, we examined AF's effects on two TNBC cell lines and the role of AhR signaling in AF sensitivity in these model cell lines.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 23%
Student > Master 6 19%
Student > Ph. D. Student 5 16%
Student > Bachelor 2 6%
Student > Postgraduate 2 6%
Other 4 13%
Unknown 5 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 19%
Biochemistry, Genetics and Molecular Biology 5 16%
Medicine and Dentistry 4 13%
Pharmacology, Toxicology and Pharmaceutical Science 3 10%
Business, Management and Accounting 1 3%
Other 4 13%
Unknown 8 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 May 2014.
All research outputs
#14,638,545
of 23,881,329 outputs
Outputs from BMC Cancer
#3,329
of 8,483 outputs
Outputs of similar age
#118,910
of 228,679 outputs
Outputs of similar age from BMC Cancer
#46
of 124 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,483 research outputs from this source. They receive a mean Attention Score of 4.4. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,679 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 124 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.