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Role of transcription regulatory sequence in regulation of gene expression and replication of porcine reproductive and respiratory syndrome virus

Overview of attention for article published in Veterinary Research, August 2017
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Title
Role of transcription regulatory sequence in regulation of gene expression and replication of porcine reproductive and respiratory syndrome virus
Published in
Veterinary Research, August 2017
DOI 10.1186/s13567-017-0445-2
Pubmed ID
Authors

Chengbao Wang, Han Meng, Yujin Gao, Hui Gao, Kangkang Guo, Fernando Almazan, Isabel Sola, Luis Enjuanes, Yanming Zhang, Levon Abrahamyan

Abstract

In order to gain insight into the role of the transcription regulatory sequences (TRSs) in the regulation of gene expression and replication of porcine reproductive and respiratory syndrome virus (PRRSV), the enhanced green fluorescent protein (EGFP) gene, under the control of the different structural gene TRSs, was inserted between the N gene and 3'-UTR of the PRRSV genome and EGFP expression was analyzed for each TRS. TRSs of all the studied structural genes of PRRSV positively modulated EGFP expression at different levels. Among the TRSs analyzed, those of GP2, GP5, M, and N genes highly enhanced EGFP expression without altering replication of PRRSV. These data indicated that structural gene TRSs could be an extremely useful tool for foreign gene expression using PRRSV as a vector.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 18%
Researcher 3 18%
Lecturer 1 6%
Other 1 6%
Student > Ph. D. Student 1 6%
Other 3 18%
Unknown 5 29%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 3 18%
Biochemistry, Genetics and Molecular Biology 3 18%
Agricultural and Biological Sciences 2 12%
Immunology and Microbiology 2 12%
Chemistry 1 6%
Other 0 0%
Unknown 6 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2017.
All research outputs
#22,764,772
of 25,382,440 outputs
Outputs from Veterinary Research
#1,199
of 1,337 outputs
Outputs of similar age
#287,019
of 327,545 outputs
Outputs of similar age from Veterinary Research
#13
of 15 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,337 research outputs from this source. They receive a mean Attention Score of 5.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.