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High-resolution measurements of the multilayer ultra-structure of articular cartilage and their translational potential

Overview of attention for article published in Arthritis Research & Therapy, March 2014
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  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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2 X users

Citations

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49 Dimensions

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Title
High-resolution measurements of the multilayer ultra-structure of articular cartilage and their translational potential
Published in
Arthritis Research & Therapy, March 2014
DOI 10.1186/ar4506
Pubmed ID
Authors

Bo He, Jian Ping Wu, Thomas Brett Kirk, John A Carrino, Chuan Xiang, Jiake Xu

Abstract

Current musculoskeletal imaging techniques usually target the macro-morphology of articular cartilage or use histological analysis. These techniques are able to reveal advanced osteoarthritic changes in articular cartilage but fail to give detailed information to distinguish early osteoarthritis from healthy cartilage, and this necessitates high-resolution imaging techniques measuring cells and the extracellular matrix within the multilayer structure of articular cartilage. This review provides a comprehensive exploration of the cellular components and extracellular matrix of articular cartilage as well as high-resolution imaging techniques, including magnetic resonance image, electron microscopy, confocal laser scanning microscopy, second harmonic generation microscopy, and laser scanning confocal arthroscopy, in the measurement of multilayer ultra-structures of articular cartilage. This review also provides an overview for micro-structural analysis of the main components of normal or osteoarthritic cartilage and discusses the potential and challenges associated with developing non-invasive high-resolution imaging techniques for both research and clinical diagnosis of early to late osteoarthritis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 99 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 18%
Student > Master 15 15%
Student > Bachelor 14 14%
Researcher 13 13%
Student > Postgraduate 7 7%
Other 15 15%
Unknown 18 18%
Readers by discipline Count As %
Engineering 28 28%
Medicine and Dentistry 11 11%
Biochemistry, Genetics and Molecular Biology 9 9%
Agricultural and Biological Sciences 7 7%
Materials Science 5 5%
Other 16 16%
Unknown 24 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 September 2014.
All research outputs
#16,046,765
of 25,371,288 outputs
Outputs from Arthritis Research & Therapy
#2,337
of 3,380 outputs
Outputs of similar age
#128,741
of 235,685 outputs
Outputs of similar age from Arthritis Research & Therapy
#24
of 58 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,380 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,685 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.