Title |
Comparison of genomic and proteomic data in recurrent airway obstruction affected horses using ingenuity pathway analysis®
|
---|---|
Published in |
BMC Veterinary Research, August 2011
|
DOI | 10.1186/1746-6148-7-48 |
Pubmed ID | |
Authors |
Julien Racine, Vinzenz Gerber, Marybeth Miskovic Feutz, C Paige Riley, Jiri Adamec, June E Swinburne, Laurent L Couetil |
Abstract |
Recurrent airway obstruction (RAO) is a severe chronic respiratory disease affecting horses worldwide, though mostly in the Northern hemisphere. Environmental as well as genetic factors strongly influence the course and prognosis of the disease. Research has been focused on characterization of immunologic factors contributing to inflammatory responses, on genetic linkage analysis, and, more recently, on proteomic analysis of airway secretions from affected horses. The goal of this study was to investigate the interactions between eight candidate genes previously identified in a genetic linkage study and proteins expressed in bronchoalveolar lavage fluid (BALF) collected from healthy and RAO-affected horses. The analysis was carried out with Ingenuity Pathway Analysis® bioinformatics software. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 50% |
Australia | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 3% |
Belgium | 1 | 3% |
Unknown | 35 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 19% |
Researcher | 6 | 16% |
Student > Doctoral Student | 5 | 14% |
Professor > Associate Professor | 3 | 8% |
Other | 2 | 5% |
Other | 4 | 11% |
Unknown | 10 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 7 | 19% |
Biochemistry, Genetics and Molecular Biology | 6 | 16% |
Veterinary Science and Veterinary Medicine | 5 | 14% |
Medicine and Dentistry | 3 | 8% |
Nursing and Health Professions | 1 | 3% |
Other | 2 | 5% |
Unknown | 13 | 35% |