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An intron polymorphism of the fibronectin gene is associated with end-stage knee osteoarthritis in a Han Chinese population: two independent case- control studies

Overview of attention for article published in BMC Musculoskeletal Disorders, May 2014
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Title
An intron polymorphism of the fibronectin gene is associated with end-stage knee osteoarthritis in a Han Chinese population: two independent case- control studies
Published in
BMC Musculoskeletal Disorders, May 2014
DOI 10.1186/1471-2474-15-173
Pubmed ID
Authors

Hsin-Yi Yang, Sui-Lung Su, Yi-Jen Peng, Chih-Chien Wang, Herng-Sheng Lee, Donald M Salter, Chian-Her Lee

Abstract

Knee osteoarthritis (OA) is a complex disease involving both biomechanical and metabolic factors that alter the tissue homeostasis of articular cartilage and subchondral bone. The catabolic activities of extracellular matrix degradation products, especially fibronectin (FN), have been implicated in mediating cartilage degradation. Chondrocytes express several members of the integrin family which can serve as receptors for FN including integrins α5β1, αvβ3, and αvβ5. The purpose of this study was to determine whether polymorphisms in the FN (FN-1) and integrin genes are markers of susceptibility to, or severity of, knee OA in a Han Chinese population.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 33 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 26%
Student > Ph. D. Student 5 15%
Student > Bachelor 3 9%
Researcher 3 9%
Other 2 6%
Other 5 15%
Unknown 7 21%
Readers by discipline Count As %
Medicine and Dentistry 8 24%
Agricultural and Biological Sciences 3 9%
Nursing and Health Professions 2 6%
Biochemistry, Genetics and Molecular Biology 2 6%
Engineering 2 6%
Other 6 18%
Unknown 11 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 May 2014.
All research outputs
#18,372,841
of 22,756,196 outputs
Outputs from BMC Musculoskeletal Disorders
#3,123
of 4,037 outputs
Outputs of similar age
#163,059
of 226,329 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#68
of 96 outputs
Altmetric has tracked 22,756,196 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,037 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,329 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 96 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.