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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Truncated and modified amyloid-beta species
|
|---|---|
| Published in |
Alzheimer's Research & Therapy, May 2014
|
| DOI | 10.1186/alzrt258 |
| Pubmed ID | |
| Authors |
Markus P Kummer, Michael T Heneka |
| Abstract |
Alzheimer's disease pathology is closely connected to the processing of the amyloid precursor protein (APP) resulting in the formation of a variety of amyloid-beta (Aβ) peptides. They are found as insoluble aggregates in senile plaques, the histopathological hallmark of the disease. These peptides are also found in soluble, mostly monomeric and dimeric, forms in the interstitial and cerebrospinal fluid. Due to the combination of several enzymatic activities during APP processing, Aβ peptides exist in multiple isoforms possessing different N-termini and C-termini. These peptides include, to a certain extent, part of the juxtamembrane and transmembrane domain of APP. Besides differences in size, post-translational modifications of Aβ - including oxidation, phosphorylation, nitration, racemization, isomerization, pyroglutamylation, and glycosylation - generate a plethora of peptides with different physiological and pathological properties that may modulate disease progression. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 1 | 25% |
| Venezuela, Bolivarian Republic of | 1 | 25% |
| United Kingdom | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 25% |
| Members of the public | 1 | 25% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 355 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | <1% |
| Belgium | 2 | <1% |
| South Africa | 1 | <1% |
| Sweden | 1 | <1% |
| Canada | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 347 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 79 | 22% |
| Student > Master | 54 | 15% |
| Student > Bachelor | 46 | 13% |
| Researcher | 40 | 11% |
| Other | 14 | 4% |
| Other | 46 | 13% |
| Unknown | 76 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 79 | 22% |
| Biochemistry, Genetics and Molecular Biology | 58 | 16% |
| Neuroscience | 58 | 16% |
| Chemistry | 33 | 9% |
| Medicine and Dentistry | 17 | 5% |
| Other | 29 | 8% |
| Unknown | 81 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 November 2023.
All research outputs
#6,333,243
of 25,374,647 outputs
Outputs from Alzheimer's Research & Therapy
#1,210
of 1,465 outputs
Outputs of similar age
#55,724
of 240,808 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#10
of 16 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 1,465 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.6. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,808 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.