Title |
Perilla Extract improves gastrointestinal discomfort in a randomized placebo controlled double blind human pilot study
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Published in |
BMC Complementary Medicine and Therapies, May 2014
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DOI | 10.1186/1472-6882-14-173 |
Pubmed ID | |
Authors |
Sybille Buchwald-Werner, Hajime Fujii, Claudia Reule, Christiane Schoen |
Abstract |
Gastrointestinal (GI) discomfort, e.g. bloating or rumbling, is a common symptom in otherwise healthy adults. Approximately 20% of the population, particularly women suffer from gastrointestinal discomfort and this affects quality of life. Recent studies discovered a link between the body and mind, called the gut-brain axis. Psychosocial factors, such as e.g. daily stress may cause altered gut physiology leading to ileum contractions and consequently gastrointestinal symptoms. In vitro and ex vivo studies clearly showed that a Perilla frutescens extract combines prokinetic, antispasmodic and anti-inflammatory effects. The aim of the intervention was to investigate the effects of the proprietary Perilla extract on GI discomfort in healthy subjects with gastrointestinal discomfort and reduced bowel movements in comparison to a placebo product. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Germany | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 61 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 8 | 13% |
Researcher | 7 | 11% |
Student > Master | 6 | 10% |
Other | 5 | 8% |
Student > Doctoral Student | 3 | 5% |
Other | 9 | 15% |
Unknown | 23 | 38% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 11 | 18% |
Agricultural and Biological Sciences | 6 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
Biochemistry, Genetics and Molecular Biology | 3 | 5% |
Chemistry | 3 | 5% |
Other | 10 | 16% |
Unknown | 25 | 41% |