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Biological function in the twilight zone of sequence conservation

Overview of attention for article published in BMC Biology, August 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)

Mentioned by

twitter
51 tweeters

Citations

dimensions_citation
24 Dimensions

Readers on

mendeley
90 Mendeley
citeulike
3 CiteULike
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Title
Biological function in the twilight zone of sequence conservation
Published in
BMC Biology, August 2017
DOI 10.1186/s12915-017-0411-5
Pubmed ID
Authors

Chris P. Ponting

Abstract

Strong DNA conservation among divergent species is an indicator of enduring functionality. With weaker sequence conservation we enter a vast 'twilight zone' in which sequence subject to transient or lower constraint cannot be distinguished easily from neutrally evolving, non-functional sequence. Twilight zone functional sequence is illuminated instead by principles of selective constraint and positive selection using genomic data acquired from within a species' population. Application of these principles reveals that despite being biochemically active, most twilight zone sequence is not functional.

Twitter Demographics

The data shown below were collected from the profiles of 51 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 90 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 22%
Researcher 16 18%
Student > Bachelor 11 12%
Student > Master 9 10%
Student > Doctoral Student 5 6%
Other 23 26%
Unknown 6 7%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 37 41%
Agricultural and Biological Sciences 30 33%
Medicine and Dentistry 2 2%
Mathematics 2 2%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 6 7%
Unknown 11 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 June 2019.
All research outputs
#978,604
of 17,897,867 outputs
Outputs from BMC Biology
#284
of 1,553 outputs
Outputs of similar age
#20,956
of 231,563 outputs
Outputs of similar age from BMC Biology
#1
of 1 outputs
Altmetric has tracked 17,897,867 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,553 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.0. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 231,563 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them