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X Demographics
Mendeley readers
Title |
Biological function in the twilight zone of sequence conservation
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Published in |
BMC Biology, August 2017
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DOI | 10.1186/s12915-017-0411-5 |
Pubmed ID | |
Authors |
Chris P. Ponting |
Abstract |
Strong DNA conservation among divergent species is an indicator of enduring functionality. With weaker sequence conservation we enter a vast 'twilight zone' in which sequence subject to transient or lower constraint cannot be distinguished easily from neutrally evolving, non-functional sequence. Twilight zone functional sequence is illuminated instead by principles of selective constraint and positive selection using genomic data acquired from within a species' population. Application of these principles reveals that despite being biochemically active, most twilight zone sequence is not functional. |
X Demographics
The data shown below were collected from the profiles of 48 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 13 | 27% |
United Kingdom | 9 | 19% |
Switzerland | 2 | 4% |
France | 2 | 4% |
Portugal | 1 | 2% |
Germany | 1 | 2% |
Spain | 1 | 2% |
India | 1 | 2% |
Canada | 1 | 2% |
Other | 0 | 0% |
Unknown | 17 | 35% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 28 | 58% |
Members of the public | 18 | 38% |
Science communicators (journalists, bloggers, editors) | 2 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 108 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 108 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 24 | 22% |
Researcher | 18 | 17% |
Student > Bachelor | 12 | 11% |
Student > Master | 10 | 9% |
Student > Doctoral Student | 6 | 6% |
Other | 24 | 22% |
Unknown | 14 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 40 | 37% |
Agricultural and Biological Sciences | 35 | 32% |
Medicine and Dentistry | 3 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
Mathematics | 2 | 2% |
Other | 8 | 7% |
Unknown | 18 | 17% |