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In case you missed it: Biological function in the twilight zone of sequence conservation https://t.co/RWiQPOIMLm
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Function vs conservation vs constraint: what can sequence conservation tell us about biological function? Chris Ponting @CGATist reviews the 'twilight zone', where, 'despite being biochemically active, most sequence is not functional' https://t.co/c7lPh3Jt
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@pknoepfler There’s strong evidence that most of it is still junk—or non-functional, to be a bit more precise. https://t.co/y1Hf4IXN10
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Biological function in the twilight zone of sequence conservation https://t.co/eMRnIZAUJN