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Overcoming multiple drug resistance mechanisms in medulloblastoma

Overview of attention for article published in Acta Neuropathologica Communications, May 2014
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Title
Overcoming multiple drug resistance mechanisms in medulloblastoma
Published in
Acta Neuropathologica Communications, May 2014
DOI 10.1186/2051-5960-2-57
Pubmed ID
Authors

Ramadhan T Othman, Ioanna Kimishi, Tracey D Bradshaw, Lisa CD Storer, Andrey Korshunov, Stefan M Pfister, Richard G Grundy, Ian D Kerr, Beth Coyle

Abstract

Medulloblastoma (MB) is the most common malignant paediatric brain tumour. Recurrence and progression of disease occurs in 15-20% of standard risk and 30-40% of high risk patients. We analysed whether circumvention of chemoresistance pathways (drug export, DNA repair and apoptotic inhibition) can restore chemotherapeutic efficacy in a panel of MB cell lines.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 98 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 29 29%
Student > Ph. D. Student 19 19%
Student > Master 15 15%
Researcher 11 11%
Student > Doctoral Student 6 6%
Other 6 6%
Unknown 13 13%
Readers by discipline Count As %
Medicine and Dentistry 36 36%
Biochemistry, Genetics and Molecular Biology 19 19%
Agricultural and Biological Sciences 13 13%
Pharmacology, Toxicology and Pharmaceutical Science 8 8%
Neuroscience 2 2%
Other 6 6%
Unknown 15 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 May 2014.
All research outputs
#18,372,841
of 22,756,196 outputs
Outputs from Acta Neuropathologica Communications
#1,228
of 1,369 outputs
Outputs of similar age
#163,146
of 226,629 outputs
Outputs of similar age from Acta Neuropathologica Communications
#14
of 18 outputs
Altmetric has tracked 22,756,196 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,369 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.8. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,629 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.