Title |
Synaptosomal-associated protein 25 (Snap-25) gene Polymorphism frequency in fibromyalgia syndrome and relationship with clinical symptoms
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Published in |
BMC Musculoskeletal Disorders, May 2014
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DOI | 10.1186/1471-2474-15-191 |
Pubmed ID | |
Authors |
Ayse Balkarli, Cem Sengül, Emre Tepeli, Huseyin Balkarli, Veli Cobankara |
Abstract |
SNAP-25 protein is contributory to plasma membrane and synaptic vesicle fusions that are critical points in neurotransmission. SNAP-25 gene is associated with behavioral symptoms, personality and psychological disorders. In addition, SNAP-25 protein can be related to different neurotransmitter functions due to its association with vesicle membrane transition and fusion. This is important because neurologic, cognitive, and psychologic disorders in fibromyalgia syndrome (FMS) can be related to this function. This relationship may be enlightening for etiopathogenesis of FMS and treatment approaches. We aimed to study a SNAP-25 gene polymorphism, which is related to many psychiatric diseases, and FMS association in this prospective study. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 25% |
Germany | 1 | 25% |
United Kingdom | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Spain | 1 | 2% |
Unknown | 64 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 15% |
Student > Bachelor | 9 | 14% |
Researcher | 7 | 11% |
Student > Doctoral Student | 7 | 11% |
Student > Postgraduate | 6 | 9% |
Other | 15 | 23% |
Unknown | 12 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 14 | 21% |
Medicine and Dentistry | 13 | 20% |
Nursing and Health Professions | 8 | 12% |
Neuroscience | 6 | 9% |
Agricultural and Biological Sciences | 3 | 5% |
Other | 7 | 11% |
Unknown | 15 | 23% |