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Mendeley readers
Title |
Molecular dissection of Wnt3a-Frizzled8 interaction reveals essential and modulatory determinants of Wnt signaling activity
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Published in |
BMC Biology, May 2014
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DOI | 10.1186/1741-7007-12-44 |
Pubmed ID | |
Authors |
Sumit Kumar, Mihaela Žigman, Trushar R Patel, Benjamin Trageser, Julia Christina Gross, Karolin Rahm, Michael Boutros, Dietmar Gradl, Herbert Steinbeisser, Thomas Holstein, Jörg Stetefeld, Suat Özbek |
Abstract |
Wnt proteins are a family of secreted signaling molecules that regulate key developmental processes in metazoans. The molecular basis of Wnt binding to Frizzled and LRP5/6 co-receptors has long been unknown due to the lack of structural data on Wnt ligands. Only recently, the crystal structure of the Wnt8-Frizzled8-cysteine-rich-domain (CRD) complex was solved, but the significance of interaction sites that influence Wnt signaling has not been assessed. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Science communicators (journalists, bloggers, editors) | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 2 | 3% |
Unknown | 61 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 16 | 25% |
Researcher | 10 | 16% |
Student > Bachelor | 8 | 13% |
Student > Master | 8 | 13% |
Student > Doctoral Student | 4 | 6% |
Other | 9 | 14% |
Unknown | 8 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 30 | 48% |
Agricultural and Biological Sciences | 15 | 24% |
Medicine and Dentistry | 3 | 5% |
Chemistry | 3 | 5% |
Neuroscience | 2 | 3% |
Other | 2 | 3% |
Unknown | 8 | 13% |