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X Demographics
Mendeley readers
Attention Score in Context
| Title |
PARalyzer: definition of RNA binding sites from PAR-CLIP short-read sequence data
|
|---|---|
| Published in |
Genome Biology, August 2011
|
| DOI | 10.1186/gb-2011-12-8-r79 |
| Pubmed ID | |
| Authors |
David L Corcoran, Stoyan Georgiev, Neelanjan Mukherjee, Eva Gottwein, Rebecca L Skalsky, Jack D Keene, Uwe Ohler |
| Abstract |
Crosslinking and immunoprecipitation (CLIP) protocols have made it possible to identify transcriptome-wide RNA-protein interaction sites. In particular, PAR-CLIP utilizes a photoactivatable nucleoside for more efficient crosslinking. We present an approach, centered on the novel PARalyzer tool, for mapping high-confidence sites from PAR-CLIP deep-sequencing data. We show that PARalyzer delineates sites with a high signal-to-noise ratio. Motif finding identifies the sequence preferences of RNA-binding proteins, as well as seed-matches for highly expressed microRNAs when profiling Argonaute proteins. Our study describes tailored analytical methods and provides guidelines for future efforts to utilize high-throughput sequencing in RNA biology. PARalyzer is available at http://www.genome.duke.edu/labs/ohler/research/PARalyzer/. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 50% |
| France | 1 | 25% |
| Australia | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
| Members of the public | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 326 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 8 | 2% |
| France | 4 | 1% |
| Germany | 4 | 1% |
| Italy | 3 | <1% |
| United Kingdom | 2 | <1% |
| Czechia | 1 | <1% |
| Sweden | 1 | <1% |
| Austria | 1 | <1% |
| China | 1 | <1% |
| Other | 3 | <1% |
| Unknown | 298 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 111 | 34% |
| Researcher | 69 | 21% |
| Student > Master | 33 | 10% |
| Student > Bachelor | 17 | 5% |
| Student > Doctoral Student | 14 | 4% |
| Other | 46 | 14% |
| Unknown | 36 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 157 | 48% |
| Biochemistry, Genetics and Molecular Biology | 69 | 21% |
| Computer Science | 27 | 8% |
| Medicine and Dentistry | 9 | 3% |
| Immunology and Microbiology | 5 | 2% |
| Other | 16 | 5% |
| Unknown | 43 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2014.
All research outputs
#3,612,279
of 25,394,764 outputs
Outputs from Genome Biology
#2,493
of 4,470 outputs
Outputs of similar age
#18,174
of 133,457 outputs
Outputs of similar age from Genome Biology
#19
of 47 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,470 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 133,457 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.