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Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels

Overview of attention for article published in Molecular Brain, May 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

Mentioned by

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1 X user
patent
1 patent

Citations

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49 Dimensions

Readers on

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41 Mendeley
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Title
Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels
Published in
Molecular Brain, May 2014
DOI 10.1186/1756-6606-7-42
Pubmed ID
Authors

Stephanie C Stotz, Lucas OM Scott, Christopher Drummond-Main, Yosef Avchalumov, Fernando Girotto, Jörn Davidsen, Maria R Gómez-Gárcia, Jong M Rho, Evgeny V Pavlov, Michael A Colicos

Abstract

Inorganic polyphosphate (polyP) is a highly charged polyanion capable of interacting with a number of molecular targets. This signaling molecule is released into the extracellular matrix by central astrocytes and by peripheral platelets during inflammation. While the release of polyP is associated with both induction of blood coagulation and astrocyte extracellular signaling, the role of secreted polyP in regulation of neuronal activity remains undefined. Here we test the hypothesis that polyP is an important participant in neuronal signaling. Specifically, we investigate the ability of neurons to release polyP and to induce neuronal firing, and clarify the underlying molecular mechanisms of this process by studying the action of polyP on voltage gated channels.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 40 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 22%
Researcher 8 20%
Student > Bachelor 4 10%
Student > Doctoral Student 3 7%
Student > Postgraduate 3 7%
Other 5 12%
Unknown 9 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 24%
Agricultural and Biological Sciences 7 17%
Neuroscience 7 17%
Medicine and Dentistry 3 7%
Chemistry 2 5%
Other 2 5%
Unknown 10 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 June 2014.
All research outputs
#6,940,528
of 22,756,196 outputs
Outputs from Molecular Brain
#326
of 1,106 outputs
Outputs of similar age
#66,413
of 226,965 outputs
Outputs of similar age from Molecular Brain
#7
of 17 outputs
Altmetric has tracked 22,756,196 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,965 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.