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Survivin safeguards chromosome numbers and protects from aneuploidy independently from p53

Overview of attention for article published in Molecular Cancer, May 2014
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Title
Survivin safeguards chromosome numbers and protects from aneuploidy independently from p53
Published in
Molecular Cancer, May 2014
DOI 10.1186/1476-4598-13-107
Pubmed ID
Authors

Ralf Wiedemuth, Barbara Klink, Katrin Töpfer, Evelin Schröck, Gabriele Schackert, Masaaki Tatsuka, Achim Temme

Abstract

Survivin, a member of the inhibitor of apoptosis (IAP) gene family, has a dual role in mitosis and in apoptosis. It is abundantly expressed in every human tumor, compared with normal tissues. During mitosis Survivin assembles with the chromosomal passenger complex and regulates chromosomal segregation. Here, we aim to explore whether interference with the mitotic function of Survivin is linked to p53-mediated G1 cell cycle arrest and affects chromosomal stability.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
Netherlands 1 3%
Unknown 30 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 47%
Student > Bachelor 3 9%
Student > Doctoral Student 2 6%
Researcher 2 6%
Professor 2 6%
Other 3 9%
Unknown 5 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 12 38%
Agricultural and Biological Sciences 10 31%
Medicine and Dentistry 2 6%
Immunology and Microbiology 1 3%
Psychology 1 3%
Other 1 3%
Unknown 5 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 June 2014.
All research outputs
#20,230,558
of 22,756,196 outputs
Outputs from Molecular Cancer
#1,477
of 1,718 outputs
Outputs of similar age
#193,093
of 227,220 outputs
Outputs of similar age from Molecular Cancer
#43
of 46 outputs
Altmetric has tracked 22,756,196 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,718 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,220 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.