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How informative is your kinetic model?: using resampling methods for model invalidation

Overview of attention for article published in BMC Systems Biology, May 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

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4 X users

Citations

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67 Mendeley
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Title
How informative is your kinetic model?: using resampling methods for model invalidation
Published in
BMC Systems Biology, May 2014
DOI 10.1186/1752-0509-8-61
Pubmed ID
Authors

Dicle Hasdemir, Huub CJ Hoefsloot, Johan A Westerhuis, Age K Smilde

Abstract

Kinetic models can present mechanistic descriptions of molecular processes within a cell. They can be used to predict the dynamics of metabolite production, signal transduction or transcription of genes. Although there has been tremendous effort in constructing kinetic models for different biological systems, not much effort has been put into their validation. In this study, we introduce the concept of resampling methods for the analysis of kinetic models and present a statistical model invalidation approach.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 1%
South Africa 1 1%
United Kingdom 1 1%
Mexico 1 1%
Spain 1 1%
United States 1 1%
Unknown 61 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 28%
Student > Ph. D. Student 18 27%
Student > Master 10 15%
Professor 3 4%
Professor > Associate Professor 3 4%
Other 8 12%
Unknown 6 9%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 12 18%
Agricultural and Biological Sciences 12 18%
Engineering 7 10%
Computer Science 5 7%
Medicine and Dentistry 5 7%
Other 18 27%
Unknown 8 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 July 2014.
All research outputs
#13,176,295
of 22,756,196 outputs
Outputs from BMC Systems Biology
#452
of 1,142 outputs
Outputs of similar age
#108,051
of 226,264 outputs
Outputs of similar age from BMC Systems Biology
#9
of 28 outputs
Altmetric has tracked 22,756,196 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,142 research outputs from this source. They receive a mean Attention Score of 3.6. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,264 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.