Title |
Comparative analysis of Klebsiella pneumoniae genomes identifies a phospholipase D family protein as a novel virulence factor
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Published in |
BMC Biology, May 2014
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DOI | 10.1186/1741-7007-12-41 |
Pubmed ID | |
Authors |
Letícia MS Lery, Lionel Frangeul, Anna Tomas, Virginie Passet, Ana S Almeida, Suzanne Bialek-Davenet, Valérie Barbe, José A Bengoechea, Philippe Sansonetti, Sylvain Brisse, Régis Tournebize |
Abstract |
Klebsiella pneumoniae strains are pathogenic to animals and humans, in which they are both a frequent cause of nosocomial infections and a re-emerging cause of severe community-acquired infections. K. pneumoniae isolates of the capsular serotype K2 are amongst the most virulent. In order to identify novel putative virulence factors that may account for the severity of K2 infections, the genome sequence of the K2 reference strain Kp52.145 was determined and compared to two K1 and K2 strains of low virulence and to the reference strains MGH 78578 and NTUH-K2044. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 50% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 50% |
Scientists | 1 | 25% |
Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | <1% |
India | 1 | <1% |
United Kingdom | 1 | <1% |
New Zealand | 1 | <1% |
United States | 1 | <1% |
Unknown | 191 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 37 | 19% |
Researcher | 30 | 15% |
Student > Bachelor | 29 | 15% |
Student > Master | 22 | 11% |
Student > Postgraduate | 10 | 5% |
Other | 25 | 13% |
Unknown | 43 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 52 | 27% |
Biochemistry, Genetics and Molecular Biology | 46 | 23% |
Immunology and Microbiology | 23 | 12% |
Medicine and Dentistry | 14 | 7% |
Engineering | 4 | 2% |
Other | 14 | 7% |
Unknown | 43 | 22% |