Title |
Cardiac findings in children with juvenile Dermatomyositis at disease presentation
|
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Published in |
Pediatric Rheumatology, July 2017
|
DOI | 10.1186/s12969-017-0182-0 |
Pubmed ID | |
Authors |
Serdar Cantez, Gil J. Gross, Ian MacLusky, Brian M. Feldman |
Abstract |
Juvenile Dermatomyositis (JDM) is a pediatric vasculopathy characterized primarily by skin and muscle involvement. Cardiac findings have been reported in children with JDM but have rarely been investigated in detail. We aimed to describe the relevant clinical and laboratory cardiac findings of a cohort of patients with JDM, followed at one centre, at disease diagnosis. We performed a retrospective review of 105 patients with JDM, followed from 1991 to 2007. Six of 70 patients (9%, 6% of the entire cohort) had abnormal electrocardiographic (ECG) findings, while 26 of 54 patients (48%, 25% of the entire cohort) had abnormal echocardiographic (echo) findings. Many of these findings were either mild or unlikely to be a result of JDM. Our findings suggest that cardiac abnormalities at JDM disease onset are frequently seen, but are rarely significant findings due to disease; however, JDM patients should be considered for screening for cardiac disease as late cardiac complications are well recognized. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 30 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 6 | 20% |
Other | 4 | 13% |
Student > Master | 4 | 13% |
Researcher | 4 | 13% |
Student > Ph. D. Student | 4 | 13% |
Other | 5 | 17% |
Unknown | 3 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 12 | 40% |
Immunology and Microbiology | 4 | 13% |
Agricultural and Biological Sciences | 2 | 7% |
Unspecified | 2 | 7% |
Nursing and Health Professions | 1 | 3% |
Other | 4 | 13% |
Unknown | 5 | 17% |