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Non-Invasive markers for hepatic fibrosis

Overview of attention for article published in BMC Gastroenterology, August 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

blogs
1 blog
twitter
1 tweeter
patent
1 patent

Citations

dimensions_citation
207 Dimensions

Readers on

mendeley
211 Mendeley
citeulike
1 CiteULike
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Title
Non-Invasive markers for hepatic fibrosis
Published in
BMC Gastroenterology, August 2011
DOI 10.1186/1471-230x-11-91
Pubmed ID
Authors

Ancha Baranova, Priyanka Lal, Aybike Birerdinc, Zobair M Younossi

Abstract

With great advancements in the therapeutic modalities used for the treatment of chronic liver diseases, the accurate assessment of liver fibrosis is a vital need for successful individualized management of disease activity in patients. The lack of accurate, reproducible and easily applied methods for fibrosis assessment has been the major limitation in both the clinical management and for research in liver diseases. However, the problem of the development of biomarkers capable of non-invasive staging of fibrosis in the liver is difficult due to the fact that the process of fibrogenesis is a component of the normal healing response to injury, invasion by pathogens, and many other etiologic factors. Current non-invasive methods range from serum biomarker assays to advanced imaging techniques such as transient elastography and magnetic resonance imaging (MRI). Among non-invasive methods that gain strongest clinical foothold are FibroScan elastometry and serum-based APRI and FibroTest. There are many other tests that are not yet widely validated, but are none the less, promising. The rate of adoption of non-invasive diagnostic tests for liver fibrosis differs from country to country, but remains limited. At the present time, use of non-invasive procedures could be recommended as pre-screening that may allow physicians to narrow down the patients' population before definitive testing of liver fibrosis by biopsy of the liver. This review provides a systematic overview of these techniques, as well as both direct and indirect biomarkers based approaches used to stage fibrosis and covers recent developments in this rapidly advancing area.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 211 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 3 1%
Germany 2 <1%
Netherlands 2 <1%
Denmark 2 <1%
Italy 1 <1%
Indonesia 1 <1%
Australia 1 <1%
India 1 <1%
Canada 1 <1%
Other 3 1%
Unknown 194 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 34 16%
Student > Ph. D. Student 32 15%
Student > Master 28 13%
Other 20 9%
Student > Postgraduate 20 9%
Other 57 27%
Unknown 20 9%
Readers by discipline Count As %
Medicine and Dentistry 105 50%
Agricultural and Biological Sciences 24 11%
Biochemistry, Genetics and Molecular Biology 16 8%
Pharmacology, Toxicology and Pharmaceutical Science 5 2%
Chemistry 4 2%
Other 18 9%
Unknown 39 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 February 2016.
All research outputs
#1,133,627
of 12,373,180 outputs
Outputs from BMC Gastroenterology
#51
of 800 outputs
Outputs of similar age
#8,819
of 89,947 outputs
Outputs of similar age from BMC Gastroenterology
#1
of 10 outputs
Altmetric has tracked 12,373,180 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 800 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 89,947 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them