Title |
Potential regenerative rehabilitation technology: implications of mechanical stimuli to tissue health
|
---|---|
Published in |
BMC Research Notes, June 2014
|
DOI | 10.1186/1756-0500-7-334 |
Pubmed ID | |
Authors |
Colleen L McHenry, Jason Wu, Richard K Shields |
Abstract |
Mechanical loads induced through muscle contraction, vibration, or compressive forces are thought to modulate tissue plasticity. With the emergence of regenerative medicine, there is a need to understand the optimal mechanical environment (vibration, load, or muscle force) that promotes cellular health. To our knowledge no mechanical system has been proposed to deliver these isolated mechanical stimuli in human tissue. We present the design, performance, and utilization of a new technology that may be used to study localized mechanical stimuli on human tissues. A servo-controlled vibration and limb loading system were developed and integrated into a single instrument to deliver vibration, compression, or muscle contractile loads to a single limb (tibia) in humans. The accuracy, repeatability, transmissibility, and safety of the mechanical delivery system were evaluated on eight individuals with spinal cord injury (SCI). |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 3% |
Unknown | 38 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 15% |
Student > Master | 5 | 13% |
Student > Bachelor | 4 | 10% |
Student > Doctoral Student | 4 | 10% |
Student > Ph. D. Student | 4 | 10% |
Other | 6 | 15% |
Unknown | 10 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Engineering | 6 | 15% |
Nursing and Health Professions | 5 | 13% |
Agricultural and Biological Sciences | 5 | 13% |
Medicine and Dentistry | 5 | 13% |
Sports and Recreations | 1 | 3% |
Other | 3 | 8% |
Unknown | 14 | 36% |