Report for: ABCC transporters mediate insect resistance to multiple Bt toxins revealed by bulk segregant analysis

Title	ABCC transporters mediate insect resistance to multiple Bt toxins revealed by bulk segregant analysis
Published in	BMC Biology, June 2014
DOI	10.1186/1741-7007-12-46
Pubmed ID	24912445
Authors	Youngjin Park, Rosa M González-Martínez, Gloria Navarro-Cerrillo, Maissa Chakroun, Yonggyun Kim, Pello Ziarsolo, Jose Blanca, Joaquin Cañizares, Juan Ferré, Salvador Herrero
Abstract	Relatively recent evidence indicates that ABCC2 transporters play a main role in the mode of action of Bacillus thuringiensis (Bt) Cry1A-type proteins. Mapping of major Cry1A resistance genes has linked resistance to the ABCC2 locus in Heliothis virescens, Plutella xylostella, Trichoplusia ni and Bombyx mori, and mutations in this gene have been found in three of these Bt-resistant strains.

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ABCC transporters mediate insect resistance to multiple Bt toxins revealed by bulk segregant analysis