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Effect of smoking and comorbidities on survival in idiopathic pulmonary fibrosis

Overview of attention for article published in Respiratory Research, August 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

news
1 news outlet
twitter
3 tweeters

Citations

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29 Dimensions

Readers on

mendeley
53 Mendeley
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Title
Effect of smoking and comorbidities on survival in idiopathic pulmonary fibrosis
Published in
Respiratory Research, August 2017
DOI 10.1186/s12931-017-0642-6
Pubmed ID
Authors

Miia Kärkkäinen, Hannu-Pekka Kettunen, Hanna Nurmi, Tuomas Selander, Minna Purokivi, Riitta Kaarteenaho

Abstract

Cigarette smoking has been associated with the risk of idiopathic pulmonary fibrosis (IPF). Certain comorbidities have been associated with reduced survival although some studies have indicated that current smokers have a longer survival than ex-smokers. Comorbidities in relation to smoking history have not been previously analyzed. Retrospective data was collected and patients were categorized according to gender and smoking habits. Comorbidities and medications were collected. Predictive values for mortality were identified by COX proportional hazard analyses. We examined 45 non-smokers (53.3% female), 66 ex-smokers (9.1% female) and 17 current smokers (17.6% female) with IPF. Current smokers were younger at baseline (58.1 ± 8.74 years) compared to non-smokers (71.4 ± 8.74, p < 0.001) and ex-smokers (72.5 ±7.95, p <0.001). Median survival of non-smokers and current smokers was longer (55.0 and 52.0 months, respectively) than that of ex-smokers (36.0 months) (p=0.028 and 0.034, respectively). In age and severity adjusted analyses, smoking was not related to survival. Cardiovascular diseases (CVD) (72.7 %) were the most common comorbidities, current smokers had more chronic obstructive pulmonary disease (COPD) and lung cancer compared to ex-smokers (p<0.001). CVD, COPD and use of insulin were related to poorer survival in adjusted analyses. Smoking seems to influence the course of disease in IPF since current smokers developed the disease at a younger age in comparison to non-smokers and ex-smokers. No significant differences in the major comorbidities were detected between IPF patients with different smoking histories. The mechanism through which smoking influences IPF progression requires further investigation.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 53 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 17%
Student > Bachelor 8 15%
Student > Ph. D. Student 6 11%
Student > Master 6 11%
Student > Doctoral Student 5 9%
Other 9 17%
Unknown 10 19%
Readers by discipline Count As %
Medicine and Dentistry 20 38%
Pharmacology, Toxicology and Pharmaceutical Science 6 11%
Agricultural and Biological Sciences 4 8%
Biochemistry, Genetics and Molecular Biology 4 8%
Computer Science 2 4%
Other 4 8%
Unknown 13 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 September 2017.
All research outputs
#1,179,416
of 11,717,557 outputs
Outputs from Respiratory Research
#121
of 1,328 outputs
Outputs of similar age
#45,123
of 264,461 outputs
Outputs of similar age from Respiratory Research
#8
of 42 outputs
Altmetric has tracked 11,717,557 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,328 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,461 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.