↓ Skip to main content

Inhibition of the checkpoint kinase Chk1 induces DNA damage and cell death in human Leukemia and Lymphoma cells

Overview of attention for article published in Molecular Cancer, June 2014
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (74th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

twitter
3 X users
patent
1 patent

Citations

dimensions_citation
49 Dimensions

Readers on

mendeley
59 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Inhibition of the checkpoint kinase Chk1 induces DNA damage and cell death in human Leukemia and Lymphoma cells
Published in
Molecular Cancer, June 2014
DOI 10.1186/1476-4598-13-147
Pubmed ID
Authors

Christopher Bryant, Kirsten Scriven, Andrew J Massey

Abstract

Chk1 forms a core component of the DNA damage response and small molecule inhibitors are currently being investigated in the clinic as cytotoxic chemotherapy potentiators. Recent evidence suggests that Chk1 inhibitors may demonstrate significant single agent activity in tumors with specific DNA repair defects, a constitutively activated DNA damage response or oncogene induced replicative stress.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 2%
United States 1 2%
France 1 2%
Unknown 56 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 24%
Researcher 9 15%
Student > Bachelor 7 12%
Other 4 7%
Student > Master 3 5%
Other 4 7%
Unknown 18 31%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 27%
Biochemistry, Genetics and Molecular Biology 15 25%
Medicine and Dentistry 6 10%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Unspecified 1 2%
Other 2 3%
Unknown 17 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2021.
All research outputs
#6,030,418
of 22,757,090 outputs
Outputs from Molecular Cancer
#409
of 1,718 outputs
Outputs of similar age
#57,103
of 229,145 outputs
Outputs of similar age from Molecular Cancer
#8
of 50 outputs
Altmetric has tracked 22,757,090 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,718 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 229,145 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.