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Total knee Arthroplasty: risk factors for allogeneic blood transfusions in the South Asian population

Overview of attention for article published in BMC Musculoskeletal Disorders, August 2017
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Title
Total knee Arthroplasty: risk factors for allogeneic blood transfusions in the South Asian population
Published in
BMC Musculoskeletal Disorders, August 2017
DOI 10.1186/s12891-017-1728-5
Pubmed ID
Authors

Syed Hamza Mufarrih, Nada Qaisar Qureshi, Arif Ali, Azeem Tariq Malik, Huda Naim, Shahryar Noordin

Abstract

Total knee arthroplasty (TKA) is the recommended treatment for end-stage knee osteoarthritis. Considering the various risks associated with intra and postoperative blood transfusions, better understanding is required with respect to the risk factors contributing to a greater possibility of blood transfusion during or after surgery. Although literature highlights several such factors, our study is among the first to identify these risk factors in the South Asian population which differs from other populations in several ways. The study consists of a review of 658 patients undergoing TKA from 2005 to 2015. Data was obtained from patient medical records and was analysed using logistic regression analysis. The relationship between each predictor and the outcome variable was calculated as an Odds ratio (OR), the threshold of significance for which was p = 0.25 and p = 0.05 for univariate and multivariable analysis respectively. The mean age of the patient population was 63 years (78% female), 25% of whom received one or more blood transfusions. Multivariable analysis revealed 5 significant independent predictors for increased risk of blood transfusions including bilateral knee surgery (OR:5.51), preoperative anemia (OR:4.15), higher ASA (American Society of Anaesthesiologists) status (3-4) (OR:1.92), female sex (OR:3.44) and BMI (Body mass index) ≤30 (OR:1.79) while increasing co-morbidities and age (>60) were found to be insignificant. The factors identified for the South Asian population are largely similar to those for other populations. Identification of high risk patients will permit the application of an international multipronged approach which not only targets the modifiable risk factors but also the decision making process and blood management protocols in order to minimize the transfusion associated risks for a patient undergoing a TKA.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 49 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 14%
Student > Bachelor 6 12%
Student > Postgraduate 3 6%
Student > Doctoral Student 2 4%
Other 2 4%
Other 7 14%
Unknown 22 45%
Readers by discipline Count As %
Medicine and Dentistry 15 31%
Nursing and Health Professions 4 8%
Engineering 3 6%
Biochemistry, Genetics and Molecular Biology 2 4%
Psychology 1 2%
Other 0 0%
Unknown 24 49%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2017.
All research outputs
#15,254,161
of 24,288,381 outputs
Outputs from BMC Musculoskeletal Disorders
#2,265
of 4,270 outputs
Outputs of similar age
#179,941
of 320,934 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#46
of 69 outputs
Altmetric has tracked 24,288,381 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,270 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,934 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.