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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The BH3 mimetic ABT-737 increases treatment efficiency of paclitaxel against hepatoblastoma
|
|---|---|
| Published in |
BMC Cancer, August 2011
|
| DOI | 10.1186/1471-2407-11-362 |
| Pubmed ID | |
| Authors |
Justus Lieber, Carmen Eicher, Julia Wenz, Bettina Kirchner, Steven W Warmann, Jörg Fuchs, Sorin Armeanu-Ebinger |
| Abstract |
The primary goal of current chemotherapy in hepatoblastoma (HB) is reduction of tumour volume and vitality to enable complete surgical resection and reduce risk of recurrence or metastatic disease. Drug resistance remains a major challenge for HB treatment. In some malignancies inhibition of anti-apoptotic pathways using small BH3 mimetic molecules like ABT-737 shows synergistic effects in combination with cystotoxic agents in vitro. Now we analysed toxicology and synergistic effects of this approach in HB cells and HB xenografts. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 3% |
| Unknown | 29 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 27% |
| Student > Master | 4 | 13% |
| Other | 3 | 10% |
| Student > Ph. D. Student | 2 | 7% |
| Student > Postgraduate | 2 | 7% |
| Other | 1 | 3% |
| Unknown | 10 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 6 | 20% |
| Medicine and Dentistry | 6 | 20% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 7% |
| Agricultural and Biological Sciences | 2 | 7% |
| Chemistry | 2 | 7% |
| Other | 2 | 7% |
| Unknown | 10 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 August 2011.
All research outputs
#20,143,522
of 22,649,029 outputs
Outputs from BMC Cancer
#6,475
of 8,235 outputs
Outputs of similar age
#113,733
of 123,839 outputs
Outputs of similar age from BMC Cancer
#64
of 103 outputs
Altmetric has tracked 22,649,029 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,235 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 123,839 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 103 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.