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Why epistasis is important for tackling complex human disease genetics

Overview of attention for article published in Genome Medicine, January 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

Mentioned by

twitter
26 tweeters
facebook
1 Facebook page
reddit
1 Redditor

Citations

dimensions_citation
103 Dimensions

Readers on

mendeley
117 Mendeley
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Title
Why epistasis is important for tackling complex human disease genetics
Published in
Genome Medicine, January 2014
DOI 10.1186/gm561
Pubmed ID
Authors

Trudy FC Mackay, Jason H Moore

Abstract

Epistasis has been dismissed by some as having little role in the genetic architecture of complex human disease. The authors argue that this view is the result of a misconception and explain why exploring epistasis is likely to be crucial to understanding and predicting complex disease.

Twitter Demographics

The data shown below were collected from the profiles of 26 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Denmark 1 <1%
Germany 1 <1%
France 1 <1%
Unknown 112 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 37 32%
Researcher 20 17%
Student > Master 19 16%
Student > Bachelor 11 9%
Professor > Associate Professor 8 7%
Other 14 12%
Unknown 8 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 49 42%
Biochemistry, Genetics and Molecular Biology 22 19%
Computer Science 11 9%
Medicine and Dentistry 10 9%
Engineering 3 3%
Other 8 7%
Unknown 14 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2020.
All research outputs
#1,826,324
of 19,039,850 outputs
Outputs from Genome Medicine
#435
of 1,261 outputs
Outputs of similar age
#21,087
of 200,471 outputs
Outputs of similar age from Genome Medicine
#6
of 16 outputs
Altmetric has tracked 19,039,850 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,261 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.3. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 200,471 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.