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Why epistasis is important for tackling complex human disease genetics

Overview of attention for article published in Genome Medicine, June 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

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24 X users
facebook
1 Facebook page
reddit
1 Redditor

Citations

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141 Dimensions

Readers on

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142 Mendeley
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Title
Why epistasis is important for tackling complex human disease genetics
Published in
Genome Medicine, June 2014
DOI 10.1186/gm561
Pubmed ID
Authors

Trudy FC Mackay, Jason H Moore

Abstract

Epistasis has been dismissed by some as having little role in the genetic architecture of complex human disease. The authors argue that this view is the result of a misconception and explain why exploring epistasis is likely to be crucial to understanding and predicting complex disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 24 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 142 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Denmark 1 <1%
Germany 1 <1%
France 1 <1%
Unknown 137 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 42 30%
Researcher 21 15%
Student > Master 21 15%
Student > Bachelor 13 9%
Professor > Associate Professor 8 6%
Other 20 14%
Unknown 17 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 53 37%
Biochemistry, Genetics and Molecular Biology 27 19%
Computer Science 13 9%
Medicine and Dentistry 11 8%
Engineering 4 3%
Other 12 8%
Unknown 22 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2020.
All research outputs
#2,696,077
of 25,374,917 outputs
Outputs from Genome Medicine
#614
of 1,585 outputs
Outputs of similar age
#26,332
of 243,428 outputs
Outputs of similar age from Genome Medicine
#8
of 22 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,585 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.8. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,428 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.