Title |
Difference in immune response in vaccinated and unvaccinated Swedish individuals after the 2009 influenza pandemic
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Published in |
BMC Infectious Diseases, June 2014
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DOI | 10.1186/1471-2334-14-319 |
Pubmed ID | |
Authors |
Isabelle Magalhaes, Mikael Eriksson, Charlotte Linde, Rashid Muhammad, Lalit Rane, Aditya Ambati, Rebecca Axelsson-Robertson, Bahareh Khalaj, Nancy Alvarez-Corrales, Giulia Lapini, Emanuele Montomoli, Annika Linde, Nancy L Pedersen, Markus Maeurer |
Abstract |
Previous exposures to flu and subsequent immune responses may impact on 2009/2010 pandemic flu vaccine responses and clinical symptoms upon infection with the 2009 pandemic H1N1 influenza strain. Qualitative and quantitative differences in humoral and cellular immune responses associated with the flu vaccination in 2009/2010 (pandemic H1N1 vaccine) and natural infection have not yet been described in detail. We designed a longitudinal study to examine influenza- (flu-) specific immune responses and the association between pre-existing flu responses, symptoms of influenza-like illness (ILI), impact of pandemic flu infection, and pandemic flu vaccination in a cohort of 2,040 individuals in Sweden in 2009-2010. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 20% |
United Kingdom | 1 | 20% |
Sweden | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 60% |
Practitioners (doctors, other healthcare professionals) | 2 | 40% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 38 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 21% |
Student > Master | 7 | 18% |
Student > Ph. D. Student | 4 | 11% |
Student > Bachelor | 3 | 8% |
Professor | 3 | 8% |
Other | 8 | 21% |
Unknown | 5 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 42% |
Immunology and Microbiology | 6 | 16% |
Agricultural and Biological Sciences | 3 | 8% |
Nursing and Health Professions | 2 | 5% |
Psychology | 2 | 5% |
Other | 3 | 8% |
Unknown | 6 | 16% |