Title |
Low plasma vitamin A concentration is associated with tuberculosis in Moroccan population: a preliminary case control study
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Published in |
BMC Research Notes, August 2017
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DOI | 10.1186/s13104-017-2737-z |
Pubmed ID | |
Authors |
Mounia Qrafli, Khalid El Kari, Hassan Aguenaou, Jamal Eddine Bourkadi, Khalid Sadki, Mohammed El Mzibri |
Abstract |
Vitamin A plays numerous roles in immune system. Its deficiency alters both the innate and adaptive immunity. Previous results reported that the micronutrients deficiency, particularly vitamin A, is observed in patients with tuberculosis. Thus, we aimed in this study to assess vitamin A concentrations in Moroccan patients with tuberculosis to set up a large efficacy study of vitamin A supplementation for TB infected patients. Plasma retinol concentration was measured by HPLC in 44 recently diagnosed TB patients and 40 healthy controls. We showed that plasma vitamin A is significantly lower in tuberculosis patients as compared to healthy controls (p < 0.0001). Moreover, no significant association was found between vitamin A deficiency and, TB severity and patients' ages. Our study confirms the association between low vitamin A levels and tuberculosis disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 29% |
Canada | 1 | 14% |
France | 1 | 14% |
United Kingdom | 1 | 14% |
Unknown | 2 | 29% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 86% |
Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 48 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 19% |
Student > Bachelor | 7 | 15% |
Student > Ph. D. Student | 6 | 13% |
Lecturer | 3 | 6% |
Student > Postgraduate | 3 | 6% |
Other | 3 | 6% |
Unknown | 17 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 21% |
Nursing and Health Professions | 5 | 10% |
Immunology and Microbiology | 4 | 8% |
Biochemistry, Genetics and Molecular Biology | 3 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 6% |
Other | 4 | 8% |
Unknown | 19 | 40% |