Title |
Acetyl-11-keto-β-boswellic acid (AKBA); targeting oral cavity pathogens
|
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Published in |
BMC Research Notes, October 2011
|
DOI | 10.1186/1756-0500-4-406 |
Pubmed ID | |
Authors |
Alsaba F Raja, Furqan Ali, Inshad A Khan, Abdul S Shawl, Daljit S Arora |
Abstract |
Boswellic acids mixture of triterpenic acids obtained from the oleo gum resin of Boswellia serrata and known for its effectiveness in the treatment of chronic inflammatory disease including peritumor edema. Boswellic acids have been extensively studied for a number of activities including anti inflammatory, antitumor, immunomodulatory, and inflammatory bowel diseases. The present study describes the antimicrobial activities of boswellic acid molecules against oral cavity pathogens. Acetyl-11-keto-β-boswellic acid (AKBA), which exhibited the most potent antibacterial activity, was further evaluated in time kill studies, mutation prevention frequency, postantibiotic effect (PAE) and biofilm susceptibility assay against oral cavity pathogens. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 64 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 16% |
Lecturer | 7 | 11% |
Student > Ph. D. Student | 7 | 11% |
Student > Master | 4 | 6% |
Student > Doctoral Student | 3 | 5% |
Other | 10 | 16% |
Unknown | 23 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 17% |
Biochemistry, Genetics and Molecular Biology | 8 | 13% |
Agricultural and Biological Sciences | 6 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Chemistry | 2 | 3% |
Other | 5 | 8% |
Unknown | 30 | 47% |