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Exploiting large-scale drug-protein interaction information for computational drug repurposing

Overview of attention for article published in BMC Bioinformatics, June 2014
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4 X users

Citations

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16 Dimensions

Readers on

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83 Mendeley
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5 CiteULike
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Title
Exploiting large-scale drug-protein interaction information for computational drug repurposing
Published in
BMC Bioinformatics, June 2014
DOI 10.1186/1471-2105-15-210
Pubmed ID
Authors

Ruifeng Liu, Narender Singh, Gregory J Tawa, Anders Wallqvist, Jaques Reifman

Abstract

Despite increased investment in pharmaceutical research and development, fewer and fewer new drugs are entering the marketplace. This has prompted studies in repurposing existing drugs for use against diseases with unmet medical needs. A popular approach is to develop a classification model based on drugs with and without a desired therapeutic effect. For this approach to be statistically sound, it requires a large number of drugs in both classes. However, given few or no approved drugs for the diseases of highest medical urgency and interest, different strategies need to be investigated.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
United Kingdom 1 1%
Netherlands 1 1%
Unknown 79 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 22%
Student > Ph. D. Student 17 20%
Student > Master 11 13%
Student > Bachelor 7 8%
Student > Doctoral Student 3 4%
Other 11 13%
Unknown 16 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 14%
Biochemistry, Genetics and Molecular Biology 10 12%
Chemistry 9 11%
Medicine and Dentistry 9 11%
Computer Science 8 10%
Other 12 14%
Unknown 23 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 June 2014.
All research outputs
#13,714,534
of 22,757,541 outputs
Outputs from BMC Bioinformatics
#4,440
of 7,272 outputs
Outputs of similar age
#114,984
of 228,326 outputs
Outputs of similar age from BMC Bioinformatics
#80
of 154 outputs
Altmetric has tracked 22,757,541 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,272 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,326 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.