Title |
Exercise induction of gut microbiota modifications in obese, non-obese and hypertensive rats
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Published in |
BMC Genomics, June 2014
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DOI | 10.1186/1471-2164-15-511 |
Pubmed ID | |
Authors |
Bernardo A Petriz, Alinne P Castro, Jeeser A Almeida, Clarissa PC Gomes, Gabriel R Fernandes, Ricardo H Kruger, Rinaldo W Pereira, Octavio L Franco |
Abstract |
Obesity is a multifactor disease associated with cardiovascular disorders such as hypertension. Recently, gut microbiota was linked to obesity pathogenesisand shown to influence the host metabolism. Moreover, several factors such as host-genotype and life-style have been shown to modulate gut microbiota composition. Exercise is a well-known agent used for the treatment of numerous pathologies, such as obesity and hypertension; it has recently been demonstrated to shape gut microbiota consortia. Since exercise-altered microbiota could possibly improve the treatment of diseases related to dysfunctional microbiota, this study aimed to examine the effect of controlled exercise training on gut microbial composition in Obese rats (n = 3), non-obese Wistar rats (n = 3) and Spontaneously Hypertensive rats (n = 3). Pyrosequencing of 16S rRNA genes from fecal samples collected before and after exercise training was used for this purpose. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 9 | 26% |
United Kingdom | 4 | 11% |
India | 2 | 6% |
Brazil | 2 | 6% |
Australia | 1 | 3% |
Russia | 1 | 3% |
Nigeria | 1 | 3% |
Switzerland | 1 | 3% |
Taiwan | 1 | 3% |
Other | 1 | 3% |
Unknown | 12 | 34% |
Demographic breakdown
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Members of the public | 18 | 51% |
Practitioners (doctors, other healthcare professionals) | 9 | 26% |
Scientists | 7 | 20% |
Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 3 | <1% |
Germany | 1 | <1% |
Ireland | 1 | <1% |
Unknown | 331 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 53 | 16% |
Student > Ph. D. Student | 43 | 13% |
Researcher | 37 | 11% |
Student > Postgraduate | 24 | 7% |
Other | 56 | 17% |
Unknown | 69 | 21% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 52 | 15% |
Biochemistry, Genetics and Molecular Biology | 40 | 12% |
Immunology and Microbiology | 25 | 7% |
Sports and Recreations | 14 | 4% |
Other | 54 | 16% |
Unknown | 83 | 25% |