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Clinical hypothermia temperatures increase complement activation and cell destruction via the classical pathway

Overview of attention for article published in Journal of Translational Medicine, June 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Good Attention Score compared to outputs of the same age and source (65th percentile)

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1 X user
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1 patent

Citations

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15 Dimensions

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37 Mendeley
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Title
Clinical hypothermia temperatures increase complement activation and cell destruction via the classical pathway
Published in
Journal of Translational Medicine, June 2014
DOI 10.1186/1479-5876-12-181
Pubmed ID
Authors

Tushar A Shah, Clifford T Mauriello, Pamela S Hair, Amandeep Sandhu, Michael P Stolz, William Thomas Bass, Neel K Krishna, Kenji M Cunnion

Abstract

Therapeutic hypothermia is a treatment modality that is increasingly used to improve clinical neurological outcomes for ischemia-reperfusion injury-mediated diseases. Antibody-initiated classical complement pathway activation has been shown to contribute to ischemia-reperfusion injury in multiple disease processes. However, how therapeutic hypothermia affects complement activation is unknown. Our goal was to measure the independent effect of temperature on complement activation, and more specifically, examine the relationship between clinical hypothermia temperatures (31-33°C), and complement activation.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 3%
Unknown 36 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 24%
Student > Master 6 16%
Student > Bachelor 4 11%
Other 3 8%
Researcher 3 8%
Other 6 16%
Unknown 6 16%
Readers by discipline Count As %
Medicine and Dentistry 12 32%
Biochemistry, Genetics and Molecular Biology 4 11%
Agricultural and Biological Sciences 4 11%
Immunology and Microbiology 2 5%
Psychology 2 5%
Other 6 16%
Unknown 7 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 December 2016.
All research outputs
#8,262,107
of 25,374,647 outputs
Outputs from Journal of Translational Medicine
#1,413
of 4,635 outputs
Outputs of similar age
#76,582
of 243,033 outputs
Outputs of similar age from Journal of Translational Medicine
#27
of 89 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 4,635 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,033 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.