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Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2

Overview of attention for article published in Journal of Translational Medicine, August 2011
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Title
Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2
Published in
Journal of Translational Medicine, August 2011
DOI 10.1186/1479-5876-9-142
Pubmed ID
Authors

María Valcárcel, Lorea Mendoza, José-Julio Hernández, Teresa Carrascal, Clarisa Salado, Olatz Crende, Fernando Vidal-Vanaclocha

Abstract

Human melanoma frequently colonizes bone marrow (BM) since its earliest stage of systemic dissemination, prior to clinical metastasis occurrence. However, how melanoma cell adhesion and proliferation mechanisms are regulated within bone marrow stromal cell (BMSC) microenvironment remain unclear. Consistent with the prometastatic role of inflammatory and angiogenic factors, several studies have reported elevated levels of cyclooxygenase-2 (COX-2) in melanoma although its pathogenic role in bone marrow melanoma metastasis is unknown.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 24%
Student > Ph. D. Student 6 18%
Student > Bachelor 4 12%
Other 3 9%
Student > Master 2 6%
Other 3 9%
Unknown 7 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 24%
Medicine and Dentistry 7 21%
Biochemistry, Genetics and Molecular Biology 5 15%
Chemistry 2 6%
Social Sciences 1 3%
Other 0 0%
Unknown 10 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 August 2011.
All research outputs
#20,145,561
of 22,651,245 outputs
Outputs from Journal of Translational Medicine
#3,279
of 3,949 outputs
Outputs of similar age
#113,842
of 123,933 outputs
Outputs of similar age from Journal of Translational Medicine
#28
of 29 outputs
Altmetric has tracked 22,651,245 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,949 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 123,933 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.