Title |
Microbiological contamination in counterfeit and unapproved drugs
|
---|---|
Published in |
BMC Pharmacology and Toxicology, June 2014
|
DOI | 10.1186/2050-6511-15-34 |
Pubmed ID | |
Authors |
Dieter Pullirsch, Julie Bellemare, Andreas Hackl, Yvon-Louis Trottier, Andreas Mayrhofer, Heidemarie Schindl, Christine Taillon, Christian Gartner, Brigitte Hottowy, Gerhard Beck, Jacques Gagnon |
Abstract |
Counterfeit and unapproved medicines are inherently dangerous and can cause patient injury due to ineffectiveness, chemical or biological contamination, or wrong dosage. Growth of the counterfeit medical market in developed countries is mainly attributable to life-style drugs, which are used in the treatment of non-life-threatening and non-painful conditions, such as slimming pills, cosmetic-related pharmaceuticals, and drugs for sexual enhancement. One of the main tasks of health authorities is to identify the exact active pharmaceutical ingredients (APIs) in confiscated drugs, because wrong API compounds, wrong concentrations, and/or the presence of chemical contaminants are the main risks associated with counterfeit medicines. Serious danger may also arise from microbiological contamination. We therefore performed a market surveillance study focused on the microbial burden in counterfeit and unapproved medicines. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Ireland | 1 | 33% |
Venezuela, Bolivarian Republic of | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 3% |
Tanzania, United Republic of | 1 | 1% |
Unknown | 70 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 12 | 16% |
Student > Master | 12 | 16% |
Student > Bachelor | 9 | 12% |
Student > Postgraduate | 5 | 7% |
Lecturer | 4 | 5% |
Other | 11 | 15% |
Unknown | 20 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Pharmacology, Toxicology and Pharmaceutical Science | 12 | 16% |
Medicine and Dentistry | 10 | 14% |
Agricultural and Biological Sciences | 8 | 11% |
Biochemistry, Genetics and Molecular Biology | 4 | 5% |
Social Sciences | 4 | 5% |
Other | 12 | 16% |
Unknown | 23 | 32% |