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Inhibitory effect of ent-Sauchinone on amyloidogenesis via inhibition of STAT3-mediated NF-κB activation in cultured astrocytes and microglial BV-2 cells

Overview of attention for article published in Journal of Neuroinflammation, July 2014
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  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • Average Attention Score compared to outputs of the same age and source

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Citations

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Title
Inhibitory effect of ent-Sauchinone on amyloidogenesis via inhibition of STAT3-mediated NF-κB activation in cultured astrocytes and microglial BV-2 cells
Published in
Journal of Neuroinflammation, July 2014
DOI 10.1186/1742-2094-11-118
Pubmed ID
Authors

Suk-Young Song, Yu Yeon Jung, Chul Ju Hwang, Hee Peom Lee, Chang Hyun Sok, Joo Hwan Kim, Sang Min Lee, Hyun Ok Seo, Byung Kook Hyun, Dong Young Choi, Sang Bae Han, Young Wan Ham, Bang Yeon Hwang, Jin Tae Hong

Abstract

ent-Sauchinone is a polyphenolic compound found in plants belonging to the lignan family. ent-Sauchinone has been shown to modulate the expression of inflammatory factors through the nuclear factor-kappa B (NF-κB) signaling pathway. It is well known that neuroinflammation is associated with amyloidogenesis. Thus, in the present study, we investigated whether ent-Sauchinone could have anti-amyloidogenic effects through the inhibition of NF-κB pathways via its anti-inflammatory property.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 19%
Student > Bachelor 4 13%
Student > Master 4 13%
Student > Doctoral Student 2 6%
Researcher 2 6%
Other 4 13%
Unknown 9 29%
Readers by discipline Count As %
Neuroscience 5 16%
Agricultural and Biological Sciences 5 16%
Pharmacology, Toxicology and Pharmaceutical Science 4 13%
Arts and Humanities 2 6%
Chemistry 2 6%
Other 3 10%
Unknown 10 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 October 2014.
All research outputs
#13,176,882
of 22,758,248 outputs
Outputs from Journal of Neuroinflammation
#1,407
of 2,619 outputs
Outputs of similar age
#108,047
of 227,685 outputs
Outputs of similar age from Journal of Neuroinflammation
#13
of 26 outputs
Altmetric has tracked 22,758,248 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,619 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,685 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.