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Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors

Overview of attention for article published in Journal for Immunotherapy of Cancer, May 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

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1 X user
patent
4 patents

Citations

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62 Dimensions

Readers on

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85 Mendeley
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Title
Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors
Published in
Journal for Immunotherapy of Cancer, May 2014
DOI 10.1186/2051-1426-2-12
Pubmed ID
Authors

By Gan Zhao, John P Vasilakos, Debra Tross, Dmitri Smirnov, Dennis M Klinman

Abstract

The TLR7/8 agonist 3M-052 and the TLR9 agonist CpG ODN both trigger innate immune responses that support the induction of tumor-specific immunity. Previous studies showed that these agonists used individually could improve the survival of mice challenged with small tumors but were of limited therapeutic benefit against large/advanced tumors.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
United States 1 1%
Unknown 83 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 29%
Researcher 24 28%
Student > Master 11 13%
Student > Doctoral Student 4 5%
Professor 4 5%
Other 4 5%
Unknown 13 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 27%
Immunology and Microbiology 14 16%
Biochemistry, Genetics and Molecular Biology 9 11%
Medicine and Dentistry 8 9%
Chemistry 6 7%
Other 10 12%
Unknown 15 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2023.
All research outputs
#4,835,465
of 25,371,288 outputs
Outputs from Journal for Immunotherapy of Cancer
#1,250
of 3,421 outputs
Outputs of similar age
#44,773
of 241,608 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#4
of 12 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,421 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.4. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,608 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.