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Human immunodeficiency virus Tat associates with a specific set of cellular RNAs

Overview of attention for article published in Retrovirology, July 2014
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  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

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2 X users

Citations

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9 Dimensions

Readers on

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30 Mendeley
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2 CiteULike
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Title
Human immunodeficiency virus Tat associates with a specific set of cellular RNAs
Published in
Retrovirology, July 2014
DOI 10.1186/1742-4690-11-53
Pubmed ID
Authors

Russell D Bouwman, Anne Palser, Chris M Parry, Eve Coulter, Jane Rasaiyaah, Paul Kellam, Richard G Jenner

Abstract

Human Immunodeficiency Virus 1 (HIV-1) exhibits a wide range of interactions with the host cell but whether viral proteins interact with cellular RNA is not clear. A candidate interacting factor is the trans-activator of transcription (Tat) protein. Tat is required for expression of virus genes but activates transcription through an unusual mechanism; binding to an RNA stem-loop, the transactivation response element (TAR), with the host elongation factor P-TEFb. HIV-1 Tat has also been shown to alter the expression of host genes during infection, contributing to viral pathogenesis but, whether Tat also interacts with cellular RNAs is unknown.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 33%
Student > Ph. D. Student 8 27%
Student > Bachelor 2 7%
Student > Master 2 7%
Student > Doctoral Student 1 3%
Other 4 13%
Unknown 3 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 30%
Biochemistry, Genetics and Molecular Biology 9 30%
Immunology and Microbiology 3 10%
Engineering 2 7%
Medicine and Dentistry 2 7%
Other 3 10%
Unknown 2 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 August 2014.
All research outputs
#15,302,478
of 22,758,248 outputs
Outputs from Retrovirology
#71
of 155 outputs
Outputs of similar age
#133,082
of 227,671 outputs
Outputs of similar age from Retrovirology
#4
of 19 outputs
Altmetric has tracked 22,758,248 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 155 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,671 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.