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The association of angiotensin-converting enzyme with biomarkers for Alzheimer’s disease

Overview of attention for article published in Alzheimer's Research & Therapy, May 2014
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Title
The association of angiotensin-converting enzyme with biomarkers for Alzheimer’s disease
Published in
Alzheimer's Research & Therapy, May 2014
DOI 10.1186/alzrt257
Pubmed ID
Authors

Hadassa M Jochemsen, Charlotte E Teunissen, Emma L Ashby, Wiesje M van der Flier, Ruth E Jones, Mirjam I Geerlings, Philip Scheltens, Patrick G Kehoe, Majon Muller

Abstract

Lower angiotensin-converting enzyme (ACE) activity could increase the risk of Alzheimer's disease (AD) as ACE functions to degrade amyloid-β (Aβ). Therefore, we investigated whether ACE protein and activity levels in cerebrospinal fluid (CSF) and serum were associated with CSF Aβ, total tau (tau) and tau phosphorylated at threonine 181 (ptau).

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 1 2%
Unknown 53 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 24%
Student > Master 12 22%
Student > Ph. D. Student 7 13%
Student > Bachelor 5 9%
Lecturer 3 6%
Other 5 9%
Unknown 9 17%
Readers by discipline Count As %
Medicine and Dentistry 7 13%
Agricultural and Biological Sciences 7 13%
Biochemistry, Genetics and Molecular Biology 6 11%
Neuroscience 6 11%
Psychology 5 9%
Other 10 19%
Unknown 13 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2014.
All research outputs
#17,286,379
of 25,374,917 outputs
Outputs from Alzheimer's Research & Therapy
#1,347
of 1,465 outputs
Outputs of similar age
#145,629
of 241,490 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#11
of 14 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,465 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.6. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,490 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.