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Ipilimumab augments antitumor activity of bispecific antibody-armed T cells

Overview of attention for article published in Journal of Translational Medicine, July 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

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1 X user
patent
5 patents

Citations

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24 Dimensions

Readers on

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58 Mendeley
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Title
Ipilimumab augments antitumor activity of bispecific antibody-armed T cells
Published in
Journal of Translational Medicine, July 2014
DOI 10.1186/1479-5876-12-191
Pubmed ID
Authors

Hiroshi Yano, Archana Thakur, Elyse N Tomaszewski, Minsig Choi, Abhinav Deol, Lawrence G Lum

Abstract

Ipilimumab is an antagonistic monoclonal antibody against cytotoxic T-lymphocyte antigen-4 (CTLA-4) that enhances antitumor immunity by inhibiting immunosuppressive activity of regulatory T cells (Treg). In this study, we investigated whether inhibiting Treg activity with ipilimumab during ex vivo T cell expansion could augment anti-CD3-driven T cell proliferation and enhance bispecific antibody (BiAb)-redirected antitumor cytotoxicity of activated T cells (ATC).

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 1 2%
Unknown 57 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 24%
Student > Ph. D. Student 9 16%
Student > Doctoral Student 7 12%
Other 5 9%
Professor 4 7%
Other 7 12%
Unknown 12 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 26%
Immunology and Microbiology 11 19%
Medicine and Dentistry 10 17%
Biochemistry, Genetics and Molecular Biology 7 12%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 1 2%
Unknown 12 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2022.
All research outputs
#4,655,567
of 23,009,818 outputs
Outputs from Journal of Translational Medicine
#756
of 4,024 outputs
Outputs of similar age
#45,583
of 226,616 outputs
Outputs of similar age from Journal of Translational Medicine
#10
of 60 outputs
Altmetric has tracked 23,009,818 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,024 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,616 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.