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Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genes

Overview of attention for article published in Gut Pathogens, June 2014
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  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

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1 X user
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1 patent

Citations

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44 Dimensions

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41 Mendeley
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Title
Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genes
Published in
Gut Pathogens, June 2014
DOI 10.1186/1757-4749-6-27
Pubmed ID
Authors

Akira Iwamoto, Toshihito Tanahashi, Rina Okada, Yukio Yoshida, Kaoru Kikuchi, Yoshihide Keida, Yoshiki Murakami, Lin Yang, Koji Yamamoto, Shin Nishiumi, Masaru Yoshida, Takeshi Azuma

Abstract

Clarithromycin (CLR) is the key drug in eradication therapy of Helicobacter pylori (H. pylori) infection, and widespread use of CLR has led to an increase in primary CLR-resistant H. pylori. The known mechanism of CLR resistance has been established in A2146G and A2147G mutations in the 23S rRNA gene, but evidence of the involvement of other genetic mechanisms is lacking. Using the MiSeq platform, whole-genome sequencing of the 19 clinical strains and the reference strain ATCC26695 was performed to identify single nucleotide variants (SNVs) of multi-drug resistant efflux pump genes in the CLR-resistant phenotype.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 17%
Student > Master 6 15%
Student > Postgraduate 4 10%
Researcher 3 7%
Other 2 5%
Other 7 17%
Unknown 12 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 17%
Medicine and Dentistry 7 17%
Agricultural and Biological Sciences 6 15%
Immunology and Microbiology 6 15%
Nursing and Health Professions 1 2%
Other 1 2%
Unknown 13 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 August 2023.
All research outputs
#7,548,829
of 24,293,076 outputs
Outputs from Gut Pathogens
#150
of 561 outputs
Outputs of similar age
#68,875
of 232,480 outputs
Outputs of similar age from Gut Pathogens
#4
of 12 outputs
Altmetric has tracked 24,293,076 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 561 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 232,480 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.