Title |
Immune enhancement activities of silk lutein extract from Bombyx mori cocoons
|
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Published in |
Biological Research, April 2014
|
DOI | 10.1186/0717-6287-47-15 |
Pubmed ID | |
Authors |
Porkaew Promphet, Sirirat Bunarsa, Manote Sutheerawattananonda, Duangkamol Kunthalert |
Abstract |
Declining immune function poses an important clinical challenge worldwide and supplementation with natural products that possessing immune enhancing properties is a promising approach for preventing or delaying immune function decline. Cocoons from yellow silkworms are a significant source of lutein, and this unexplored silk extract could be a viable alternative source for dietary lutein. This study assessed immunomodulatory activities of the silk lutein extract. Female BALB/c mice orally received lutein, either as silk or marigold extracts (10 or 20 mg/kg daily), or vehicle only (1% tween 80 in PBS pH 7.4) for 4 weeks. Natural killer (NK) cell activity, specific antibody production, lymphocyte subpopulations, mitogen-induced lymphocyte proliferation, and cytokine production were examined. |
X Demographics
Geographical breakdown
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Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 5 | 18% |
Student > Master | 4 | 14% |
Student > Bachelor | 3 | 11% |
Lecturer | 2 | 7% |
Student > Postgraduate | 2 | 7% |
Other | 5 | 18% |
Unknown | 7 | 25% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 9 | 32% |
Biochemistry, Genetics and Molecular Biology | 3 | 11% |
Medicine and Dentistry | 2 | 7% |
Mathematics | 1 | 4% |
Chemical Engineering | 1 | 4% |
Other | 2 | 7% |
Unknown | 10 | 36% |